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Science chat with Sanzh Schaz and Sfou:

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Spoiler<schazer> so out of curiosity Sanzh
<schazer> what kind of thing are you trying to lay a claim on exactly
<schazer> is it a meme
<schazer> are you trying to patent a meme
<TheBlueAvenger> You should patent a meme.
<sfou> glorious
<sfou> just slap a 2 million dollar lawsuit on anyone who posts a misspelled lolcat
<schazer> parody is a thing though
<Sanzh> "A method of increasing yield of active protein during translation of a protein from a source organism in a heterologous host by adjusting translation kinetics of mRNA encoding the protein"
<schazer> fuck ok lemme uh
<TheBlueAvenger> ...wow.
<Sanzh> lol
<schazer> go get coffee so I cna read that without my eyeballs sliding off it
<TheBlueAvenger> Like,
<Sanzh> ha ha welcome to my life
<Sanzh> at least I'm using my degree
<TheBlueAvenger> I know what those words mean individually
<TheBlueAvenger> but all together?
* TheBlueAvenger shakes her head grimly
<schazer> what is "active protein"
<schazer> is that like, enzymes, or stuff that does shit rather than being structural ,or
<Sanzh> it's like activated almonds
<schazer> lmao
<schazer> so best as I understand this
<Sanzh> https://www.google.com/patents/US20130149699
<schazer> this is micro-viagra for mRNA
<Sanzh> here's the application
<schazer> that makes it get jiggier with the ribosomes
<Sanzh> i think so
<Sanzh> it's made by the guy who discovered RNA interference
<schazer> so you get more activated almonds out of your amino acid soup
<Sanzh> i think it's like that, yeah
<schazer> is the viagra an actual chemical, or a training regime, or some kind of prayer
<sfou> you missed the part about hetrologous hosts
<sfou> and translation kinetics
<schazer> "translation kinetics" is to my understanding, the physical properties of the molecules that are involved in the translation process
<sfou> so like
<Sanzh> i'll be honest schazer
<Sanzh> i have no fuckin' idea
<sfou> throw the protein harder at the thing and it will eat more protein
<sfou> it's basically like a nourishment bullet
<schazer> wherein translation is where you feed a strand of mRNA (butt or face) through a ribosome (photocopier) which uses those instructions to join up a specific chain of amino acids (2 dimensional rendition of butt or face) which then becomes folded into a protein (paper airplane)
<sfou> a device to fire high-velocity nourishment bullets
<sfou> the hunger-sniper
<schazer> this is my high quality science metaphor
<schazer> I'm laying a claim on this shit do not steal
<schazer> so translation kinetics is like, maybe, in this case, a stool
<schazer> so it's easier to get on and off the photocopier safely
<sfou> wait
<sfou> doesn't it just mean that you slam your face or butt harder at the photocopier
<sfou> or like, just adjust the speed and angle
<schazer> no, because that'll damage the mRNA
<schazer> I really think this is some kind of stepladder he's invented
<schazer> or maybe handrails to hold onto
<sfou> like gently rub your buttcheeks against the glass without squishing them so that you get a good 3D image rather than an inferior squished copy
<schazer> I dunno, I think part of the charm of photocopying your face/butt is to get the squished look
<schazer> like if you wanted an accurate rendition you should just take a photo
<sfou> but then you wouldn't need the handles you could just sit on the thing
<sfou> and there's no need for a patent
<schazer> no, this is about making the copying process easier
<schazer> it's already possible, but we've invented a thing to make it more efficient
<sfou> ahh! i get ya.
<schazer> so, a stepladder/stool so you can get on and off the photocopier easier
<schazer> so you can hit the controls to actually print it properly
<sfou> beautiful
<schazer> Sanzh how many standard amino acids out of 20 do you give my explanation
<sfou> brb
<schazer> oh ok! I just looked up what heterologous hosts are
<schazer> they are cells that are producing a mRNA sequence->amino acid sequence->protein that it normally wouldn't
<schazer> so someone's genetically engineered the thing so it has this "foreign" DNA in it
<schazer> a fantastic example is E. coli producing insulin
<Sanzh> i'm gonna go grab dinner
<Sanzh> see you guys later :>
<schazer> Sanzh no
<schazer> wait
<schazer> tell me how good my science is
<Sanzh> iunno
<schazer> aw
<Sanzh> i'd say like maybe an aspartic acid out of 20
<schazer> woooooooo
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